Search results - ORA - Oxford University Research Archive

1

Thesis

Structure and function of trimeric intracellular cation channels (TRIC) and ryanodine receptors (RyR)

Hu, J
2021

2

Conference item

Biophysical characteristics of TRIC-A and TRIC-B channels and their regulation of RYR2: calcium signaling and excitation–contraction in cardiac, skeletal and smooth muscle

Hu, J, Venturi, E, Sigalas, C, et al.
2022-09-05

3

Journal article

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca2+ and Mg2+

Wilson, AD, Hu, J, Sigalas, C, et al.
2021-11-09

4

Thesis

Investigation into pathophysiological mechanisms that alter ryanodine receptor function in cardiovascular disease

Wilson, A
2020

5

Thesis

Mechanisms underlying statin-induced modulation of ryanodine receptors

Lindsay, C
2019

6

Journal article

FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

Venturi, E, Galfré, E, O'Brien, F, et al.
2014-02-01

7

Journal article

FKBP12 is a high affinity, reversible activator of RyR2, and FKBP12.6 antagonises its actions

Sitsapesan, R, Pitt, SJ, Venturi, E, et al.
2010-01-26

8

Journal article

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

Bushell, SR, Pike, ACW, Falzone, ME, et al.
2019-09-02

9

Conference item

Impaired ligand regulation of native RyR2 channels in the catecholaminergic polymorphic ventricular tachycardia mutation, RyR2-V2475F(+/−)

Wilson, A, Venturi, E, Sigalas, C, et al.
2019-02-15

10

Journal article

Enhanced activity of multiple TRIC‐B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents

O'Brien, F, Eberhardt, D, Witschas, K, et al.
2019-03-25

11

Journal article

Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength

Elbaz, M, Ruiz, A, Bachmann, C, et al.
2019-05-02

12

Journal article

Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour

Lindsay, C, Sitsapesan, M, Chen, W, et al.
2018-10-09

13

Thesis

Characterisation of novel cardiac and skeletal ion channels on intracellular Ca2+ stores.

Eberhardt, D
2018

14

Conference item

Statins bind to cardiac ryanodine receptor (RyR2) channels to alter opening frequency

Wilson, A, Lindsay, C, Venturi, E, et al.
2018-02-06

15

Conference item

Atorvastatin activates skeletal RyR1 channels: towards reducing statin side-effects

Lindsay, C, Venturi, E, Russell, A, et al.
2018-02-06

16

Journal article

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform

Venturi, E, Lindsay, C, Lotteau, S, et al.
2017-12-26

17

Journal article

Ca2+-calmodulin increases RyR2 open probability yet reduces ryanoid association with RyR2

Sigalas, C, Mayo-Martin, M, Jane, D, et al.
2009-10-01

18

Journal article

Is there something fishy about the regulation of the ryanodine receptor in the fish heart?

Shiels, H, Sitsapesan, R
2015-08-16

19

Journal article

Connecting two-pore channel structure with single channel permeability measurements

Eberhardt, D, Sitsapesan, R
2016-06-01

20

Journal article

FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6.

Galfré, E, Pitt, S, Venturi, E, et al.
2012-02-21

21

Journal article

Synthesis of the Ca2+-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling

Lin, W, Bolton, E, Cortopassi, W, et al.
2017-05-01

22

Journal article

Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC-A

El-Ajouz, S, Venturi, E, Witschas, K, et al.
2017-05-23

23

Journal article

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)

Grieben, M, Pike, A, Shintre, C, et al.
2016-12-19

24

Thesis

Biophysical characterisation of the mechanisms regulating sarcoplasmic reticulum K+ channel gating

O'Brien, F
2015

25

Journal article

TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model.

Venturi, E, Matyjaszkiewicz, A, Pitt, S, et al.
2013-08-01

26

Journal article

Mitsugumin 23 forms a massive bowl-shaped assembly and cation-conducting channel

Venturi, E, Mio, K, Nishi, M, et al.
2011-03-07

27

Journal article

Ca(2+)-calmodulin can activate and inactivate cardiac ryanodine receptors.

Sigalas, C, Bent, S, Kitmitto, A, et al.
2009-03-01

28

Journal article

TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.

Pitt, S, Funnell, T, Sitsapesan, M, et al.
2010-11-01

29

Journal article

Charade of the SR K+-channel: two ion-channels, TRIC-A and TRIC-B, masquerade as a single K+-channel.

Pitt, S, Park, K, Nishi, M, et al.
2010-07-01