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Randomized trial of the effects of cholesterol-lowering with simvastatin on peripheral vascular and other major vascular outcomes in 20,536 people with peripheral arterial disease and other high-risk conditions

Abstract:

Objectives The Heart Protection Study (HPS) provides an opportunity to assess directly the effects of cholesterol-lowering therapy on major vascular events (defined as myocardial infarction, coronary death, stroke, or revascularization) in patients with peripheral arterial disease (PAD). In addition, the effects on peripheral vascular events (ie, non-coronary revascularization, aneurysm repairs, major amputations or PAD deaths) can be assessed.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jvs.2006.12.054

Authors


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Institution:
University of Oxford
Role:
Author

Contributors

Medical Research Council More from this funder
British Heart Foundation More from this funder
Merck & Co. More from this funder
Roche Vitamins Ltd. More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Journal of Vascular Surgery Journal website
Volume:
45
Issue:
4
Pages:
645-654
Publication date:
2007-04-01
DOI:
ISSN:
0741-5214
Language:
English
Keywords:
Subjects:
UUID:
uuid:0095d98e-2a4c-419f-80bf-c127c9b1d9e3
Local pid:
ora:8890
Deposit date:
2014-08-26

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