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Journal article

Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells--implication for placental cell fusion.

Abstract:

CD98 heavy chain (CD98hc), expressed at high levels in developing human trophoblasts, is an integral membrane protein with multiple N-linked glycosylation sites and known to be important for cell fusion, adhesion, and amino acid transport. Western blotting and flow cytometry were used to study the effect of brefeldin A, an inhibitor of protein translocation through the Golgi, on CD98hc in the human placental trophoblast cell line BeWo. Although brefeldin A treatment caused increased cell surf...

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Publication status:
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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
Journal:
FEBS journal
Volume:
274
Issue:
11
Pages:
2715-2727
Publication date:
2007-06-01
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Source identifiers:
113572
Language:
English
Keywords:
Pubs id:
pubs:113572
UUID:
uuid:0362b701-ac71-4970-b132-1ede3591ad4e
Local pid:
pubs:113572
Deposit date:
2012-12-19

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