Journal article
Structure-based classification defines the discrete conformational classes adopted by the arenaviral GP1
- Abstract:
-
The emergence of Old and New World arenaviruses from rodent reservoirs persistently threatens human health. The GP1 subunit of the envelope-displayed arenaviral glycoprotein spike complex, GPC, mediates host-cell recognition and is an important determinant of cross-species transmission. Previous structural analyses of Old World arenaviral GP1 glycoproteins, alone and in complex with a cognate GP2 subunit, have revealed that GP1 adopts two distinct conformational states, distinguished by diffe...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- American Society of Microbiology Publisher's website
- Journal:
- Journal of Virology Journal website
- Volume:
- 93
- Issue:
- 1
- Pages:
- e01048-18
- Publication date:
- 2018-12-10
- Acceptance date:
- 2018-09-28
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Pmid:
-
30305351
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:927654
- UUID:
-
uuid:03f8b729-1737-43ed-bb4d-e2c650a340e6
- Local pid:
- pubs:927654
- Deposit date:
- 2018-12-06
Terms of use
- Copyright holder:
- Pryce et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Pryce et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
- Licence:
- CC Attribution (CC BY)
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