[Reduced risk of complications associated with severe acute (necrotizing) pancreatitis by administration of antibiotics; results from a literature review]

Journal article

OBJECTIVE: To determine the role of antibiotics in patients with acute pancreatitis. DESIGN: Literature review. METHOD: A Medline search for randomised clinical trials (RCTs) during the period 1990-1999 was carried out using the key words 'pancreatitis', 'acute' and 'antibiotics'. Outcome measures were pancreas-related infection, sepsis and death. RESULTS: Four RCTs were identified. Control groups were not given antibiotics. Based on the pooled data, the differences in risk in favour of the g...

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Authors: Bosscha, K; Vos, A; Visser, MR; Berger, P; van Dullemen, H

• Journal: Nederlands tijdschrift voor geneeskunde
• Volume: 145
• Issue: 41
• Pages: 1982-1985
• Publication date: 2001-10-01
• EISSN: 1876-8784
• ISSN: 0028-2162
• Language: Dutch; Flemish
• Keywords: Humans; Pancreatitis, Acute Necrotizing; Anti-Bacterial Agents; Sepsis; Pancreatic Diseases; Netherlands; Risk; Mortality; Randomized Controlled Trials as Topic