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The Impact of IPTi and IPTc Interventions on Malaria Clinical Burden – In Silico Perspectives

Abstract:

Background: Clinical management of malaria is a major health issue in sub-Saharan Africa. New strategies based on intermittent preventive treatment (IPT) can tackle disease burden by simultaneously reducing frequency of infections and life-threatening illness in infants (IPTi) and children (IPTc), while allowing for immunity to build up. However, concerns as to whether immunity develops efficiently in treated individuals, and whether there is a rebound ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0006627

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Role:
Author
ORCID:
0000-0002-9318-2581
More by this author
Role:
Author
ORCID:
0000-0002-1454-4979
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Wadham College
Role:
Author
ORCID:
0000-0002-6523-185X
Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
4
Issue:
8
Pages:
e6627
Publication date:
2009-08-13
Acceptance date:
2009-07-03
DOI:
EISSN:
1932-6203
Pmid:
19675675
Source identifiers:
134557
Language:
English
Keywords:
Pubs id:
pubs:134557
UUID:
uuid:04fd7fd2-d664-4df6-a62c-1237ca779aac
Local pid:
pubs:134557
Deposit date:
2019-02-05

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