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Journal article

Associations between cardiac irradiation and survival in patients with non-small cell lung cancer: Validation and new discoveries in an independent dataset

Abstract:

Introduction In ‘IDEAL-6′ patients (N = 78) treated for locally-advanced non-small-cell lung cancer using isotoxically dose-escalated radiotherapy, overall survival (OS) was associated more strongly with VLAwall-64-73-EQD2, the left atrial (LA) wall volume receiving 64–73 Gy equivalent dose in 2 Gy fractions (EQD2), than with whole-heart irradiation measures. Here we test this in an independent cohort ‘OX-RT’ (N = 64) treated routinely.

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/j.radonc.2021.10.016

Authors


Publisher:
Elsevier Publisher's website
Journal:
Radiotherapy and Oncology Journal website
Volume:
165
Pages:
119-125
Publication date:
2021-10-26
Acceptance date:
2021-10-19
DOI:
ISSN:
0167-8140
Language:
English
Keywords:
Pubs id:
1204277
Local pid:
pubs:1204277
Deposit date:
2021-11-01

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