Journal article icon

Journal article

Distinct actin cytoskeleton behaviour in primary and immortalised T-cells

Abstract:

Cytoskeletal actin dynamics are crucial for the activation of T-cells. Immortalised Jurkat T-cells have been the model system of choice to examine and correlate the dynamics of the actin cytoskeleton and the immunological synapse leading to T-cell activation. However, it has remained unclear whether immortalised cellular systems, such as Jurkat T-cells can recapitulate the cytoskeletal behaviour of primary T-cells. Studies delineating the cytoskeletal behaviour of Jurkat T-cells in comparison...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1242/jcs.232322

Authors


More by this author
Role:
Author
ORCID:
0000-0002-6585-3237
More by this author
Role:
Author
ORCID:
0000-0002-1804-7451
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Oxford college:
Balliol College
Role:
Author
ORCID:
0000-0002-8712-7471
Publisher:
Company of Biologists Publisher's website
Journal:
Journal of Cell Science
Volume:
133
Issue:
5
Article number:
jcs232322
Publication date:
2019-08-14
Acceptance date:
2019-07-19
DOI:
EISSN:
1477-9137
ISSN:
0021-9533
Pmid:
31413071
Source identifiers:
1046383
Language:
English
Keywords:
Pubs id:
pubs:1046383
UUID:
uuid:0645e0d4-630f-4c58-bb2b-c6a5d993fb1c
Local pid:
pubs:1046383
Deposit date:
2019-10-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP