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Evaluation of acute supplementation with the ketone ester (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate (deltaG) in healthy volunteers by cardiac and skeletal muscle 31P magnetic resonance spectroscopy

Abstract:

In this acute intervention study, we investigated the potential benefit of ketone supplementation in humans by studying cardiac phosphocreatine to adenosine-triphosphate ratios (PCr/ATP) and skeletal muscle PCr recovery using phosphorus magnetic resonance spectroscopy (31P-MRS) before and after ingestion of a ketone ester drink. We recruited 28 healthy individuals: 12 aged 23–70 years for cardiac 31P-MRS, and 16 aged 60–75 years for skeletal muscle 31P-MRS. Baseline and post-intervention rest...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3389/fphys.2022.793987

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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Physiology Journal website
Volume:
13
Article number:
793987
Publication date:
2022-01-31
Acceptance date:
2022-01-05
DOI:
EISSN:
1664-042X
Language:
English
Keywords:
Pubs id:
1237202
Local pid:
pubs:1237202
Deposit date:
2022-02-02

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