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Journal article

The relationship between blood flow impairment and oxygen depletion in acute ischemic stroke imaged with magnetic resonance imaging

Abstract:

Oxygenation-sensitive spin relaxation time T2' and relaxation rate R2' (1/T2') are presumed to be markers of the cerebral oxygen extraction fraction (OEF) in acute ischemic stroke. In this study we investigate the relationship of T2'/R2' with dynamic susceptibility contrast-based relative cerebral blood flow (rCBF) in acute ischemic stroke to assess their plausibility as surrogate markers of ischemic penumbra. Twenty-one consecutive patients with internal carotid artery and/or middle cerebral...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1177/0271678x17732448

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Parkinson’s UK More from this funder
Monument Trust More from this funder
National Institute for Health Research More from this funder
Publisher:
SAGE Publications Publisher's website
Journal:
Journal of Cerebral Blood Flow and Metabolism Journal website
Volume:
39
Issue:
3
Pages:
454-465
Publication date:
2017-09-20
Acceptance date:
2017-08-24
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Pmid:
28929836
Source identifiers:
729919
Language:
English
Keywords:
Pubs id:
pubs:729919
UUID:
uuid:09d916b0-1f07-4473-8302-c7b5da962adc
Local pid:
pubs:729919
Deposit date:
2017-09-21

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