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Journal article

Immunogenicity and induction of immunological memory of the heptavalent pneumococcal conjugate vaccine in preterm UK infants

Abstract:

Data on the immunogenicity and memory induction of pneumococcal conjugate vaccines in very preterm infants is limited. We vaccinated 69 full term and 68 preterm infants (median gestational age (GA) 30 weeks) with a 7-valent pneumococcal conjugate vaccine (PCV7) at 2/3/4 months of age, followed by a plain polysaccharide booster at 12 months of age. IgG-GMC (ELISA) was significantly lower in preterm infants to six vaccine serotypes (ST) at 2 months and 5 months of age, to five ST at 12 months o...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
"St George's University of London, UK", "University Children's Hospital, Düsseldorf, Germany"
Department:
Paediatric Infectious Diseases,Department of General Paediatrics
Role:
Author
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Institution:
University of Oxford
Research group:
Oxford Vaccine Group
Role:
Author
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Institution:
"Hope Hospital, Salford, UK"
Role:
Author
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Institution:
"St George's University of London"
Department:
Division of Child Health and Vaccine Institute
Role:
Author
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Institution:
"St George's University of London"
Department:
Division of Child Health and Vaccine Institute
Role:
Author
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Wyeth Vaccines More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
25
Issue:
2
Pages:
264-271
Publication date:
2007-01-01
DOI:
ISSN:
0264-410X
Language:
English
Keywords:
Subjects:
UUID:
uuid:0c0fc5d8-fc64-4f43-ab66-252fa85620cc
Local pid:
ora:3196
Deposit date:
2010-01-08

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