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Development of a refined tenocyte expansion culture technique for tendon tissue engineering.

Abstract:

The aim of this study was to efficiently expand less differentiated tenocytes with minimum use of fetal bovine serum (FBS) for tenocyte-based tendon tissue engineering. To achieve this goal, human tenocytes were cultured in different concentrations of FBS and combinations of growth factors PDGFBB , IGF-1 and bFGF. A number of growth factors were selected that could support tenocyte expansion at reduced differentiated state with minimum FBS usage. Results showed that the expansion of the tenoc...

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Publication status:
Published

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Publisher copy:
10.1002/term.1597

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
Journal of tissue engineering and regenerative medicine
Volume:
8
Issue:
12
Pages:
955-962
Publication date:
2014-12-01
DOI:
EISSN:
1932-7005
ISSN:
1932-6254
Source identifiers:
352459
Language:
English
Keywords:
Pubs id:
pubs:352459
UUID:
uuid:0c5ff107-6628-4781-a532-ca2c0cedafbf
Local pid:
pubs:352459
Deposit date:
2013-11-17

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