Journal article
Transcriptomic analysis of inflammatory cardiomyopathy identifies molecular signatures of disease and informs in silico prediction of a network-based rationale for therapy
- Abstract:
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Inflammatory cardiomyopathy covers a group of diseases characterized by inflammation and dysfunction of the heart muscle. The immunosuppressive agents such as prednisolone, azathioprine and cyclosporine are modestly effective treatments, but a molecular rationale underpinning such therapy or the development of new therapeutic strategies is lacking. We aimed to develop a network-based approach to identify therapeutic targets for inflammatory cardiomyopathy from the evolving myocardial transcri...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 3.0MB)
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- Publisher copy:
- 10.3389/fimmu.2021.640837
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 12
- Article number:
- 640837
- Publication date:
- 2021-03-05
- Acceptance date:
- 2021-02-12
- DOI:
- EISSN:
-
1664-3224
- Pmid:
-
33746983
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1169481
- Local pid:
- pubs:1169481
- Deposit date:
- 2021-05-12
Terms of use
- Copyright holder:
- K Singh et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 Singh, Fang, Davies, Wright, Lockstone, Williams, Ciháková, Knight and Bhattacharya. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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