Thesis icon

Thesis

The biology of ELTD1/ADGRL4: a novel regulator of tumour angiogenesis

Abstract:

Background: Our laboratory identified ELTD1, an orphan GPCR belonging to the adhesion GPCR family (aGPCR), as a novel regulator of angiogenesis and a potential anti-cancer therapeutic target. ELTD1 is normally expressed in both endothelial cells and vascular smooth muscle cells and expression is significantly increased in the tumour vasculature. The aim of this project was to analyse ELTD1’s function in endothelial cells and its role in breast cancer.

Method...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Oxford college:
Balliol College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Examiner
Department:
Rudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, University of Leipzig, Germany
Role:
Examiner
More from this funder
Funding agency for:
Favara, DM
More from this funder
Funding agency for:
Favara, DM
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP