Thesis icon

Thesis

Amphetamine sensitization animal model for schizophrenia and drug addiction: study of learning, memory and spontaneous behaviours

Abstract:

Amphetamine sensitization induces neuro-adaptations in the cortico-limbic-striatal circuit. Consequently, it disrupts reward processing and incentive salience attribution to behavioural stimuli. It is used as a model for aspects of drug addiction and positive symptoms in schizophrenia. However, it is unclear whether it models cognitive impairment and negative symptoms, which often represent an unmet medical need.

Amphetamine sensitization was confirmed by testing the mice used on ...

Expand abstract

Actions


Authors


More by this author
Division:
MSD
Department:
Experimental Psychology
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP