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The interplay between metabolic alterations, diastolic strain rate and exercise capacity in mild heart failure with preserved ejection fraction: a cardiovascular magnetic resonance study

Abstract:
Background Heart failure (HF) is characterized by altered myocardial substrate metabolism which can lead to myocardial triglyceride accumulation (steatosis) and lipotoxicity. However its role in mild HF with preserved ejection fraction (HFpEF) is uncertain. We measured myocardial triglyceride content (MTG) in HFpEF and assessed its relationships with diastolic function and exercise capacity. Methods Twenty seven HFpEF (clinical features of HF, left ventricul... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12968-018-0511-6

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0002-0601-3510
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Expand authors...
Wellcome Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Journal of Cardiovascular Magnetic Resonance Journal website
Volume:
20
Article number:
88
Publication date:
2018-12-24
Acceptance date:
2018-11-27
DOI:
EISSN:
1532-429X
ISSN:
1097-6647
Pmid:
30580760
Source identifiers:
954785
Language:
English
Keywords:
Pubs id:
pubs:954785
UUID:
uuid:0dc75c07-6b07-49be-b54d-c99bcb6ee198
Local pid:
pubs:954785
Deposit date:
2019-01-23

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