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Journal article

Improved outcome of 131I-mIBG treatment through combination with external beam radiotherapy in the SK-N-SH mouse model of neuroblastoma

Abstract:

Purpose: To assess the efficacy of different schedules for combining external beam radiotherapy (EBRT) with molecular radiotherapy (MRT) using 131I-mIBG in the management of neuroblastoma.

Materials and Methods: Balb/c nu/nu mice bearing SK-N-SH neuroblastoma xenografts were assigned to five treatment groups: 131I-mIBG 24h after EBRT, EBRT 6 days after 131I-mIBG, EBRT alone, 131I-mIBG alone and control (untreated). A total of 56 mice were assigned to 3 studies. Study 1: Ve...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.radonc.2017.05.002

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Radiotherapy and Oncology Journal website
Volume:
124
Issue:
3
Pages:
488-495
Publication date:
2017-06-05
Acceptance date:
2017-05-04
DOI:
EISSN:
1879-0887
ISSN:
0167-8140
Source identifiers:
698192
Pubs id:
pubs:698192
UUID:
uuid:0e7b83d5-c413-46be-93f2-9065680126d3
Local pid:
pubs:698192
Deposit date:
2017-06-02

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