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Thesis

Investigation of the potential of PorA and FetA as meningococcal vaccine components

Abstract:

In the search for a vaccine providing comprehensive protection against meningococcal disease, one vaccine currently under development contains the immunogenic proteins PorA and FetA in meningococcal outer membrane vesicles (OMVs). To achieve high levels of coverage against disease-causing isolates, the antigenic variability of these proteins could be overcome using knowledge of meningococcal epidemiology and population structure. In this study, the possible implications of variable expression...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
Hertford College
Role:
Author

Contributors

Division:
MPLS
Department:
Zoology
Role:
Supervisor
Division:
MPLS
Department:
Zoology
Role:
Supervisor
More from this funder
Funding agency for:
Sanders, H
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:0eb395b0-6ee4-4765-9b91-004d3a7cb1a6
Local pid:
ora:8684
Deposit date:
2014-06-25

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