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Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells.

Abstract:

The single channel properties of TASK-like oxygen-sensitive potassium channels were studied in rat carotid body type 1 cells. We observed channels with rapid bursting kinetics, active at resting membrane potentials. These channels were highly potassium selective with a slope conductance of 14-16 pS, values similar to those reported for TASK-1. In the absence of extracellular divalent cations, however, single channel conductance increased to 28 pS in a manner similar to that reported for TASK-...

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Publication status:
Published

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Publisher copy:
10.1152/ajplung.00010.2003

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
American journal of physiology. Lung cellular and molecular physiology
Volume:
286
Issue:
1
Pages:
L221-L230
Publication date:
2004-01-01
DOI:
EISSN:
1522-1504
ISSN:
1040-0605
Source identifiers:
312259

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