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[Current knowledge on the genetic factors involved in moyamoya disease].

Abstract:

Moyamoya disease (MMD) is characterized by progressive stenosis and occlusion of the terminal portion of the bilateral carotid arteries as well as arterial collateral vessels. The etiology of MMD, however, remains unknown. Several pieces of evidence suggest the involvement of genetic factors in MMD: over 10% of MMD patients have affected blood relatives; concordance in the affection status has been proven in 80% of identical twins; and there is an ethnic predisposition to MMD, the incidence o...

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Journal:
Brain and nerve = Shinkei kenkyu no shinpo
Volume:
60
Issue:
11
Pages:
1261-1269
Publication date:
2008-11-01
EISSN:
1344-8129
ISSN:
1881-6096
Source identifiers:
311496
Language:
Japanese
Keywords:
Pubs id:
pubs:311496
UUID:
uuid:10002c0d-285f-4202-bb30-4131f7dfe124
Local pid:
pubs:311496
Deposit date:
2012-12-19

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