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Inter-species horizontal transfer resulting in core-genome and niche-adaptive variation within Helicobacter pylori

Abstract:

Background: Horizontal gene transfer is central to evolution in most bacterial species. The detection of exchanged regions is often based upon analysis of compositional characteristics and their comparison to the organism as a whole. In this study we describe a new methodology combining aspects of established signature analysis with textual analysis approaches. This approach has been used to analyze the two available genome sequences of H. pylori. Results: This gene-by-gene analysis reveals a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2164-6-9

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Bacterial Pathogenesis and Functional Genomics Group
Role:
Author
More by this author
Institution:
University of Warwick
Department:
Department of Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Warwick
Department:
Department of Computer Science
Role:
Author
More from this funder
Funding agency for:
Saunders, N
Publisher:
BioMed Central Publisher's website
Journal:
BMC Genomics Journal website
Volume:
6
Article number:
9
Publication date:
2005-01-01
DOI:
ISSN:
1471-2164
Language:
English
Keywords:
Subjects:
UUID:
uuid:1011acd1-d976-439e-8a20-d72372deff4b
Local pid:
ora:1779
Deposit date:
2008-03-14

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