Journal article
A PCR assay to quantify patterns of HBV transcription
- Abstract:
-
Hepatitis B virus (HBV) is the prototype member of the family Hepadnaviridae and replicates via episomal copies of a covalently closed circular DNA (cccDNA) genome of approximately 3.2 kb. The chromatinization of this small viral genome, with overlapping open reading frames and regulatory elements, suggests an important role for epigenetic pathways to regulate HBV transcription. However, the host pathways that regulate HBV transcription and the temporal nature of promoter usage in infe...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- Microbiology Society Publisher's website
- Journal:
- Journal of General Virology Journal website
- Volume:
- 102
- Issue:
- 3
- Article number:
- 001373
- Publication date:
- 2019-12-17
- Acceptance date:
- 2019-11-27
- DOI:
- EISSN:
-
1465-2099
- ISSN:
-
0022-1317
- Pmid:
-
31846416
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1079552
- Local pid:
- pubs:1079552
- Deposit date:
- 2020-06-17
Terms of use
- Copyright holder:
- D’Arienzo et al.
- Copyright date:
- 2019
- Rights statement:
- © 2019 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License.
- Licence:
- CC Attribution (CC BY)
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