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Journal article

Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels.

Abstract:

TWIK-related K(+) 1 (TREK1) potassium channels are members of the two-pore domain potassium channel family and contribute to background potassium conductances in many cell types, where their activity can be regulated by a variety of physiologic and pharmacologic mediators. Fenamates such as FFA (flufenamic acid; 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid), MFA [mefenamic acid; 2-(2,3-dimethylphenyl)aminobenzoic acid], NFA [niflumic acid; 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic aci...

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Publication status:
Published

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Publisher copy:
10.1124/mol.113.091199

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Journal:
Molecular pharmacology
Volume:
85
Issue:
5
Pages:
671-681
Publication date:
2014-05-01
DOI:
EISSN:
1521-0111
ISSN:
0026-895X
Source identifiers:
458608
Language:
English
Keywords:
Pubs id:
pubs:458608
UUID:
uuid:1065cfd0-1263-440e-840b-ede79484d57c
Local pid:
pubs:458608
Deposit date:
2014-06-17

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