Thesis
The role of protein kinase C in platelet activation
- Abstract:
-
The protein kinase C (PKC) superfamily is a key regulator in platelet activation with individual isoforms playing distinct roles. This thesis focuses on the role of the novel PKC isoforms downstream of several agonists using both pharmacological and genetic approaches and human and mouse platelets. Quantification of the protein levels of PKC isoforms identified different levels of the five major PKC isoforms expressed in human platelets and also differences between levels of the same isof...
Expand abstract
Actions
Funding
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:114582b8-185a-41f5-958c-77038fb185df
- Local pid:
- ora:10663
- Deposit date:
- 2015-03-19
Terms of use
- Copyright holder:
- Unsworth, AJ
- Copyright date:
- 2012
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record