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Journal article

Mini viral RNAs act as innate immune agonists during influenza virus infection

Abstract:

The molecular processes that determine the outcome of influenza virus infection in humans are multifactorial and involve a complex interplay between host, viral and bacterial factors1. However, it is generally accepted that a strong innate immune dysregulation known as ‘cytokine storm’ contributes to the pathology of infections with the 1918 H1N1 pandemic or the highly pathogenic avian influenza viruses of the H5N1 subtype2,3,4. The RNA sensor retinoic acid-inducible gene I (RIG-I) plays an i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41564-018-0240-5

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Dunn School of Pathology
Role:
Author
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Funding agency for:
Bauer, D
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Funding agency for:
Fodor, E
Grant:
MR/R009945/1
Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Microbiology Journal website
Volume:
3
Pages:
1234–1242
Publication date:
2018-09-17
Acceptance date:
2018-08-07
DOI:
EISSN:
2058-5276
Source identifiers:
896583
Pubs id:
pubs:896583
UUID:
uuid:1188ff9d-ef0c-4d45-8e40-d05e76a24077
Local pid:
pubs:896583
Deposit date:
2018-08-07

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