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Response to highly active antiretroviral therapy varies with age: the UK and Ireland Collaborative HIV Paediatric Study.

Abstract:

OBJECTIVE: To evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy (HAART) in previously untreated children. DESIGN: Cohort study. METHODS: We examined the association between age at HAART initiation, and CD4 and HIV-1 RNA response using logistic and Cox regression, adjusting for sex, route of infection and pre-HAART values. RESULTS: CD4% increases of > 10% at 6 months were more likely in younger children [odds ratio (OR...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
AIDS (London, England)
Volume:
18
Issue:
14
Pages:
1915-1924
Publication date:
2004-09-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Source identifiers:
423366

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