Journal article
Comparative life cycle transcriptomics revises Leishmania mexicana genome annotation and links a chromosome duplication with parasitism of vertebrates
- Abstract:
-
Leishmania spp. are protozoan parasites that have two principal life cycle stages: the motile promastigote forms that live in the alimentary tract of the sandfly and the amastigote forms, which are adapted to survive and replicate in the harsh conditions of the phagolysosome of mammalian macrophages. Here, we used Illumina sequencing of poly-A selected RNA to characterise and compare the transcriptomes of L. mexicana promastigotes, axenic amastigotes and intracellular amastigotes. These data ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Royal Society
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Funding agency for:
Gluenz, E
Grant:
Royal Society University Research Fellow
+ Queen's College, Oxford
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Funding agency for:
Kelly, S
Grant:
Leverhulme Trust Early Career Fellowship
+ Leverhulme Trust
More from this funder
Funding agency for:
Kelly, S
Grant:
Leverhulme Trust Early Career Fellowship
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 11
- Issue:
- 10
- Pages:
- e1005186
- Publication date:
- 2015-10-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
Item Description
- Language:
- English
- Pubs id:
-
pubs:579529
- UUID:
-
uuid:123e31b6-4af9-4b7c-b9ea-3af829827ff7
- Local pid:
- pubs:579529
- Source identifiers:
-
579529
- Deposit date:
- 2016-01-14
Terms of use
- Copyright holder:
- Fiebig et al
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Fiebig et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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