Journal article
Crystallization and preliminary X-ray analysis of mouse RANK and its complex with RANKL.
- Abstract:
-
The interaction between the TNF-family molecule receptor activator of NF-kappaB ligand (RANKL) and its receptor RANK induces osteoclast formation, activation and survival in the process of bone remodelling. RANKL-RANK also plays critical roles in T-cell/dendritic cell communication and lymph-node formation and in a variety of pathologic conditions such as tumour-cell migration and bone metastasis. Both the ectodomain of mouse RANKL and the extracellular domain of mouse RANK have been cloned, ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1107/s1744309109015735
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Bibliographic Details
- Journal:
- Acta crystallographica. Section F, Structural biology and crystallization communications
- Volume:
- 65
- Issue:
- Pt 6
- Pages:
- 597-600
- Publication date:
- 2009-06-01
- DOI:
- EISSN:
-
1744-3091
- ISSN:
-
1744-3091
- Source identifiers:
-
14086
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:14086
- UUID:
-
uuid:12cefa00-8dbb-4922-a6f2-98208bb363d9
- Local pid:
- pubs:14086
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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