Journal article
Mechanisms of Yersinia YopO kinase substrate specificity.
- Abstract:
-
Yersinia bacteria cause a range of human diseases, including yersiniosis, Far East scarlet-like fever and the plague. Yersiniae modulate and evade host immune defences through injection of Yersinia outer proteins (Yops) into phagocytic cells. One of the Yops, YopO (also known as YpkA) obstructs phagocytosis through disrupting actin filament regulation processes - inhibiting polymerization-promoting signaling through sequestration of Rac/Rho family GTPases and by using monomeric actin as bait ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.4MB)
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- Publisher copy:
- 10.1038/srep39998
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Authors
Funding
Agency for Science, Technology and Research
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Nanyang Technological University
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National University of Singapore
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 7
- Pages:
- 39998
- Publication date:
- 2017-01-01
- Acceptance date:
- 2016-11-30
- DOI:
- ISSN:
-
2045-2322
- Source identifiers:
-
670961
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:670961
- UUID:
-
uuid:12df50c7-a2f9-459f-bbc8-7cbff7d34fb8
- Local pid:
- pubs:670961
- Deposit date:
- 2017-01-25
Terms of use
- Copyright holder:
- Grimes et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017 This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/© Te Author(s) 2017
- Licence:
- CC Attribution (CC BY)
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