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Influenza A(H1N1)pdm09 but not A(H3N2) virus infection induces durable sero-protection: results from the Ha Nam cohort

Abstract:

BACKGROUND:
The extent to which influenza recurrence depends upon waning immunity from prior-infection is undefined. We used antibody titres of Ha-Nam cohort participants to estimate protection curves and decay trajectories.
METHODS:
270 households participated in influenza-like-illness surveillance and provided blood at intervals spanning RTPCR-confirmed transmission. Sera were tested in haemagglutination inhibition assay. Infection was defined as RTPCR+ influenza-like-illness and/...

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Publication status:
In press
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/infdis/jiaa293

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Publisher:
Oxford University Press Publisher's website
Journal:
The Journal of Infectious Diseases Journal website
Place of publication:
United States
Publication date:
2020-06-02
Acceptance date:
2020-05-25
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pmid:
32484513
Language:
English
Keywords:
Pubs id:
1109820
Local pid:
pubs:1109820
Deposit date:
2021-02-11

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