Journal article icon

Journal article

Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations.

Abstract:

CMV establishes a lifelong persistent infection, and viral immune-modulating strategies are important in facilitating this. A particularly diverse CD8 T cell response develops as a result of this host-virus détente, with the CMV-specific memory T cell pool displaying unique functions and phenotypes. To gain insight into the factors that regulate CMV-specific CD8 T cell responses, we examined the influence of the B7-CD28 costimulatory pathway on magnitude, kinetics, and phenotype. Initial expa...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.4049/jimmunol.1003231

Authors


Expand authors...
Journal:
Journal of Immunology
Volume:
186
Issue:
7
Pages:
3874-3881
Publication date:
2011-04-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Source identifiers:
120190

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP