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Journal article

Combination strategies to improve targeted radionuclide therapy

Abstract:

In recent years, targeted radionuclide therapy (TRT) has emerged as a promising strategy for cancer treatment. In contrast to conventional radiotherapy, TRT delivers ionising radiation to tumours in a targeted manner, reducing the dose that healthy tissues are exposed to. Existing TRT strategies include the use of 177Lu-DOTATATE and 131I-MIBG, FDA-approved agents for the treatment of neuroendocrine tumours, and 177Lu-PSMA, which is being investigated for the treatment of prostate cancer. Alth...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2967/jnumed.120.248062

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
ORCID:
0000-0001-9521-3890
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Publisher:
Society of Nuclear Medicine Publisher's website
Journal:
Journal of Nuclear Medicine Journal website
Volume:
61
Issue:
11
Pages:
1544-1552
Publication date:
2020-10-09
Acceptance date:
2020-09-10
DOI:
EISSN:
2159-662X
ISSN:
0161-5505
Language:
English
Keywords:
Pubs id:
1132074
Local pid:
pubs:1132074
Deposit date:
2020-09-14

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