Thesis icon

Thesis

Proteomics-aided search for extracellular matrix signatures of colorectal hepatic metastases ex vivo

Abstract:

Hepatic metastases are one of the most dangerous consequences of colorectal cancer, and their occurrence often results in poor prognosis and death. There is a need to improve survival and quality of life for patients with colorectal liver metastases.

In this work, we utilised mass-spectrometry method to identify proteins characteristic of mouse colorectal liver metastasis matrisome and further confirmed the expression of some of them in liver metastasis by immunohistochemistry.

... Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Research group:
Ruth Muschel Group
Oxford college:
Jesus College
Role:
Author

Contributors

Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Supervisor
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Supervisor
More from this funder
Funding agency for:
Yuzhalin, A
Publication date:
2014
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:1487cfb0-ecc4-4b21-a593-a9b9f4271f77
Local pid:
ora:10075
Deposit date:
2015-02-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP