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Thesis

CEA-targeted monoclonal antibody therapy in colorectal cancer

Abstract:

Introduction

The adjuvant treatment of colorectal cancer (CRC) has seen little improvement in terms of mortality of the disease in the last 40 years. There has been a resurgence in research into the use of monoclonal antibodies in the treatment of CRC. Carcinoembryonic antigen (CEA) is a useful target in cancer immunotherapy. The distribution of CEA in CRC differs from that in normal colorectal tissue. In normal colorectal tissue CEA is found only on the luminal surface of the cell ...

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Institution:
University of Oxford
Oxford college:
Green Templeton College
Role:
Author
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Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author

Contributors

Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Supervisor
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Supervisor
More from this funder
Funding agency for:
Conaghan, P
Publication date:
2009
Type of award:
DM
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:149eb061-c563-4e22-9e07-8992b144c0fc
Local pid:
ora:11602
Deposit date:
2015-06-08

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