Journal article icon

Journal article

Electrostatic and functional analysis of the seven-bladed WD beta-propellers

Abstract:

β-propeller domains composed of WD repeats are highly ubiquitous and typically used as multi-site docking platforms to coordinate and integrate the activities of groups of proteins. Here, we have used extensive homology modelling of the WD40-repeat family of seven-bladed β-propellers coupled with subsequent structural classification and clustering of these models to define subfamilies of β-propellers with common structural, and probable, functional characteristics. We show that it is possible...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:

Authors


More by this author
Institution:
"University of Oxford", "University of Leicester"
Department:
Department of Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
"University of North Carolina"
Department:
Department of Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Oxford college:
Kellogg College
Role:
Author
More from this funder
Funding agency for:
Downing, A
Publisher:
Libertas Academica Publisher's website
Journal:
Evolutionary Bioinformatics Journal website
Volume:
4
Pages:
203-216
Publication date:
2008-06-01
ISSN:
1176-9343
Language:
English
Subjects:
UUID:
uuid:1535de2e-d979-4ed0-aa7c-7a0ed2253278
Local pid:
ora:3158
Deposit date:
2009-12-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP