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Thesis

Investigating the structure and mechanism of GPCR activation through mass spectrometry approaches

Abstract:

G protein-coupled receptors (GPCRs) comprise the largest class of membrane proteins that regulate human physiological functions in response to chemical or physical signals from the external environment. However, a more detailed understanding of the GPCR activation process is required due to the complexity of the receptor ligand selectivity and interactions that take place during activation and coupling. The major aim of the thesis is to investigate the GPCR signalling and activation by utiliz...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Sub-Department of Physical and Theoretical Chemistry
Oxford college:
Exeter College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Supervisor

DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
Subjects:
Deposit date:
2025-10-22

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