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Thesis

An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans

Abstract:

The identification of genetic variants such as single nucleotide polymorphisms (SNPs), which affect cancer progression, survival and response to treatments could help in the design of better prevention and treatment strategies. Genome-wide association studies (GWAS) have provided the first step of identifying SNPs associating with cancer risk. However, identifying the causal SNPs responsible for the associations has proven challenging, and GWAS have not been successful for time-to-event ph...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Ludwig Institute for Cancer Research, Dr. Gareth Bond
Oxford college:
Queen's College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:16f4482e-7f83-46c9-88d9-583c4154e044
Local pid:
ora:9662
Deposit date:
2015-01-06

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