Journal article
Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization
- Abstract:
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Transmission of hemorrhagic fever New World arenaviruses from their rodent reservoirs to human populations poses substantial public health and economic dangers. These zoonotic events are enabled by the specific interaction between the New World arenaviral attachment glycoprotein, GP1, and cell surface human transferrin receptor (hTfR1). Here, we present the structural basis for how a mouse-derived neutralizing antibody (nAb), OD01, disrupts this interaction by targeting the receptor-binding s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 135.0KB)
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- Publisher copy:
- 10.1073/pnas.1702127114
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Authors
Funding
Bibliographic Details
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences Journal website
- Volume:
- 114
- Issue:
- 27
- Pages:
- 7031–7036
- Publication date:
- 2017-06-19
- Acceptance date:
- 2017-05-23
- DOI:
- ISSN:
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1091-6490
- Source identifiers:
-
701540
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:701540
- UUID:
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uuid:189ff624-d2c8-478b-8c14-8690aa4d9659
- Local pid:
- pubs:701540
- Deposit date:
- 2017-06-22
Terms of use
- Copyright holder:
- Zeltina et al
- Copyright date:
- 2017
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from National Academy of Sciences at: doi: 10.1073/pnas.1702127114
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