Raw data for "Hundt et al., Direct observation of the molecular mechnism underlying protein polymerization, Science Advances 2022"
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- University of Oxford
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See "Actin_manuscript_ORA/Readme.txt" and "Actin_manuscript_ORA/Raw_videos_and_MP_analyses/Comments.txt". Protein assembly is a main route to generating complexity in living systems. Revealing the underlying molecular details is challenging because of the intrinsic heterogeneity of species ranging from few to hundreds of molecules. Here, we use mass photometry to quantify and monitor the full range of actin oligomers during polymerization with single-molecule sensitivity. We find that tradit... Expand documentation
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