Journal article icon

Journal article

Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins

Abstract:

The proteasome is responsible for selective degradation of proteins. It exists in mammalian cells under four main subtypes, which differ by the combination of their catalytic subunits: the standard proteasome (β1–β2–β5), the immunoproteasome (β1i–β2i–β5i) and the two intermediate proteasomes (β1–β2–β5i and β1i–β2–β5i). The efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins remains unclear. Using cells expressing exclusively one proteasome subtype, we obse...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/s41598-020-71550-5

Authors


More by this author
Role:
Author
ORCID:
0000-0002-9920-6927
More by this author
Role:
Author
ORCID:
0000-0001-5794-4422
More by this author
Role:
Author
ORCID:
0000-0003-2680-8932
Expand authors...
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
10
Issue:
1
Article number:
15765
Publication date:
2020-09-25
Acceptance date:
2020-08-19
DOI:
EISSN:
2045-2322
Language:
English
Keywords:
Pubs id:
1135512
Local pid:
pubs:1135512
Deposit date:
2020-09-29

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP