Journal article
Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
- Abstract:
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The proteasome is responsible for selective degradation of proteins. It exists in mammalian cells under four main subtypes, which differ by the combination of their catalytic subunits: the standard proteasome (β1–β2–β5), the immunoproteasome (β1i–β2i–β5i) and the two intermediate proteasomes (β1–β2–β5i and β1i–β2–β5i). The efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins remains unclear. Using cells expressing exclusively one proteasome subtype, we obse...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 1.5MB)
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- Publisher copy:
- 10.1038/s41598-020-71550-5
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 10
- Issue:
- 1
- Article number:
- 15765
- Publication date:
- 2020-09-25
- Acceptance date:
- 2020-08-19
- DOI:
- EISSN:
-
2045-2322
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1135512
- Local pid:
- pubs:1135512
- Deposit date:
- 2020-09-29
Terms of use
- Copyright holder:
- JA Habib et al.
- Copyright date:
- 2020
- Rights statement:
- © The Author(s) 2020. Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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