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In vitro migration assays

Abstract:

The timely recruitment of innate and adaptive immune cells to sites of inflammation and repair is essential for host defense against pathogens and repair of damaged tissues. The development of bioassays such as in vitro chemotaxis assays played an important role in the original purification of chemoattractant cytokines including interleukin-1 and the CC and CXC chemokines. The earliest chemotaxis methods were based on the principle of the Boyden chamber, first described in 1962. In this chapt...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
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Role:
Author
ORCID:
0000-0002-3224-3651
Publisher:
Humana Press Publisher's website
Volume:
1784
Issue:
May 2018
Pages:
197-214
Series:
Methods in Molecular Biology
Host title:
Methods in molecular biology
Publication date:
2018-05-15
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Pmid:
29761401
Source identifiers:
853098
Language:
English
Keywords:
Pubs id:
pubs:853098
UUID:
uuid:19a2a297-a1ab-4c26-a7da-3c68da5d810a
Local pid:
pubs:853098
Deposit date:
2018-07-04

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