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Journal article

Exosomal miRNAs as cancer biomarkers and therapeutic targets

Abstract:

Intercommunication between cancer cells and their surrounding and distant environments is key to survival, progression and metastasis of the tumour. Exosomes play a role in this communication process. MicroRNA (miRNA) expression is frequently dysregulated in tumour cells, and is reflected by distinct exosomal miRNA (ex-miRNA) profiles isolated from the bodily fluids of cancer patients. Here, the potential of ex-miRNA as a cancer biomarker and therapeutic target is critically analysed. Exosome...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3402/jev.v5.31292

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More from this funder
Funding agency for:
Wilson, C
Grant:
C38302/A12278
More from this funder
Funding agency for:
Wilson, C
Grant:
C38302/A12278
More from this funder
Funding agency for:
Wilson, C
Grant:
C38302/A12278
More from this funder
Funding agency for:
Wilson, C
Grant:
C38302/A12278
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Publisher:
Co-Action Publishing Publisher's website
Journal:
Journal of Extracellular Vesicles Journal website
Volume:
5
Article number:
31292
Publication date:
2016-07-19
Acceptance date:
2016-06-09
DOI:
EISSN:
2001-3078
ISSN:
2001-3078
Source identifiers:
629978
Keywords:
Pubs id:
pubs:629978
UUID:
uuid:19e0b401-4692-4bab-925e-b81ef9fa231f
Local pid:
pubs:629978
Deposit date:
2016-06-26

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