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Thesis

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors

Abstract:

The vaccine field generally accepts that the induction of high-titre antibodies will be necessary to prevent the invasion of erythrocytes utilising vaccines targeting the blood-stage of malaria. Protein-in-adjuvant formulations are commonly used to achieve such responses. However, their clinical development can be limited by the reactogenicity of some of the most potent pre-clinical adjuvants and the cost and complexity of licensing new adjuvants for human use. Work in this thesis describe...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Jenner Institute
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:19e5644d-63e0-4f73-9b98-f869660a6494
Deposit date:
2016-11-15

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