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Journal article

Comparison of linear and non-linear implementation of the compartmental tissue uptake model for dynamic contrast-enhanced magnetic resonance imaging

Abstract:

Background Fitting tracer kinetic models using linear methods is much faster than using their nonlinear counterparts, although this comes often at the expense of reduced accuracy and precision. The aim of this study was to derive and compare the performance of the linear compartmental tissue uptake (CTU) model with its nonlinear version with respect to their percentage error and precision. Theory and Methods The linear and nonlinear CTU models were initially compared using simulations with v...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mrm.26324

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
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Engineering and Physical Sciences Research Council More from this funder
Cancer Research UK More from this funder
Danish Society of Clinical Oncology More from this funder
Danish Cancer Society More from this funder
Publisher:
Wiley Publisher's website
Journal:
Magnetic Resonance in Medicine Journal website
Volume:
77
Issue:
6
Pages:
2414–2423
Publication date:
2016-09-01
Acceptance date:
2016-06-08
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Source identifiers:
627868
Keywords:
Pubs id:
pubs:627868
UUID:
uuid:19f79e7c-4e7b-4d58-9b56-f0336115b86d
Local pid:
pubs:627868
Deposit date:
2016-06-14

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