Journal article
Neurotransmitter switching coupled to β-adrenergic signaling in sympathetic neurons in prehypertensive states
- Abstract:
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Single or combinatorial administration of β-blockers is a mainstay treatment strategy for conditions caused by sympathetic overactivity. Conventional wisdom suggests that the main beneficial effect of β-blockers includes resensitization and restoration of β1-adrenergic signaling pathways in the myocardium, improvements in cardiomyocyte contractility, and reversal of ventricular sensitization. However, emerging evidence indicates that another beneficial effect of β-blockers in disease may ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Version of record, pdf, 7.6MB)
-
- Publisher copy:
- 10.1161/hypertensionaha.118.10844
Authors
Funding
Bibliographic Details
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Hypertension Journal website
- Volume:
- 71
- Issue:
- 6
- Pages:
- 1226-1238
- Publication date:
- 2018-04-23
- Acceptance date:
- 2018-03-26
- DOI:
- EISSN:
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1524-4563
- ISSN:
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0194-911X
- Pmid:
-
29686017
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:844771
- UUID:
-
uuid:1bcf4df7-eefd-463b-8a92-71e819943688
- Local pid:
- pubs:844771
- Deposit date:
- 2018-05-04
Terms of use
- Copyright holder:
- Bardsley et al
- Copyright date:
- 2018
- Notes:
-
© 2018 The Authors. Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access
article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the
original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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