Journal article
Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
- Abstract:
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Background: Macrophages (Mθ) play a central role in the innate immune response and in the pathology of chronic inflammatory diseases. Macrophages treated with Th2-type cytokines such as Interleukin-4 (IL-4) and Interleukin-13 (IL-13) exhibit an altered phenotype and such alternatively activated macrophages are important in the pathology of diseases characterised by allergic inflammation including asthma and atopic dermatitis. The CC chemokine Thymus and Activation-Regulated Chemokine (TARC/CC...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1186/1471-2199-7-45
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Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- BMC Molecular Biology Journal website
- Volume:
- 7
- Article number:
- 45
- Publication date:
- 2006-01-01
- DOI:
- ISSN:
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1471-2199
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:1c513f70-440d-4da2-9477-8650c79f2865
- Local pid:
- ora:2295
- Deposit date:
- 2008-09-04
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- Copyright holder:
- Liddiard et al;
- Copyright date:
- 2006
- Notes:
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Citation: Liddiard, K. et al. (2006). 'Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter', BMC Molecular Biology, 7:45. [Available at http://www.biomedcentral.com/1471-2199/7/45]
Copyright 2006 Liddiard et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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