Thesis icon

Thesis

Selection along the HIV-1 genome through the CTL mediated immune response

Abstract:

During human immunodeficiency virus 1 (HIV-1) infection, the viral population is in constant battle with the host immune system. The cytotoxic T-lymphocyte (CTL) response, a branch of the adaptive immune response, is implicated in viral control and can drive viral evolution in the infected host population. Endogenous viral peptides, or ‘epitopes’, are presented to CTLs by human leukocyte antigen (HLA) class I molecules on the surface of infected cells where they may be identified as non-se...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Oxford college:
St Cross College
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:1cd57b15-485d-4f5a-8a1c-7702a355c597
Local pid:
ora:10382

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP