Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

Journal article

Background
The burden and influence of health-care associated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use of rapid SARS-CoV-2 sequencing combined with detailed epidemiological analysis to investigate health-care associated SARS-CoV-2 infections and inform infection control measures.
Methods
In this prospective surveillance study, we set up rapid SARS-CoV-2 nanopore sequencing ... Expand abstract

Authors: Meredith, LW; Hamilton, WL; Warne, B; Houldcroft, CJ; Hosmillo, M

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Elsevier Publisher's website
• Journal: The Lancet Infectious Diseases Journal website
• Volume: 20
• Issue: 11
• Pages: 1263-1271
• Publication date: 2020-11-01
• Acceptance date: 2020-06-22
• DOI: 10.1016/s1473-3099(20)30562-4
• EISSN: 1474-4457
• ISSN: 1473-3099
• Pmid: 32679081
• Language: English
• Keywords: coronavirus infections; adolescent; young adult; humans; whole genome sequencing; FFR; middle aged; aged; pandemics; male; cross Infection; adult; phylogeny; child, preschool; polymerase chain reaction; female; aged, 80 and over; SARS-CoV-2; polymorphism, single Nucleotide; infant, newborn; prospective studies; COVID-19; infection control; genome, viral; betacoronavirus; Patient Safety; England; pneumonia, viral