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Resolving fine cardiac structures in rats with high-resolution diffusion tensor imaging.

Abstract:

Cardiac architecture is fundamental to cardiac function and can be assessed non-invasively with diffusion tensor imaging (DTI). Here, we aimed to overcome technical challenges in ex vivoDTI in order to extract fine anatomical details and to provide novel insights in the 3D structure of the heart. An integrated set of methods was implemented in ex vivorat hearts, including dynamic receiver gain adjustment, gradient system scaling calibration, prospective adjustment of diffusion gradients, and ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/srep30573

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Funding agency for:
Burton, R
Grant:
109371/Z/15/Z
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Funding agency for:
Burton, R
Grant:
109371/Z/15/Z
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Funding agency for:
Schneider, J
Grant:
FS/12/17/29532
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
6
Pages:
30573
Publication date:
2016-07-01
Acceptance date:
2016-07-04
DOI:
ISSN:
2045-2322
Source identifiers:
634183
Language:
English
Keywords:
Pubs id:
pubs:634183
UUID:
uuid:1e0a3057-7a97-41f0-b0ee-7d9d56912a72
Local pid:
pubs:634183
Deposit date:
2016-08-01

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