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Thesis

The biological characterisation of triple negative breast cancer in cyclic hypoxia

Abstract:

Regions of insufficient oxygen, hypoxia, occur in most solid tumours, including breast cancer. Hypoxia occurs due to malformed tumour vasculature and uncontrolled cell proliferation and is associated with therapy resistance and an overall poor patient prognosis. Of all the breast cancer subtypes, hypoxia is particularly evident in triple negative breast cancer (TNBC). A wealth of evidence suggests that cyclic hypoxia is commonplace in solid tumours and is associated with the most aggressive d...

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Division:
MSD
Department:
Oncology
Oxford college:
St Catherine's College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Deposit date:
2022-02-02

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